The Zebrafish:
The zebrafish embryo offers a useful system for investigating mechanisms that control development in vertebrates.  The embryos can be readily obtained in large numbers, are optically clear, and permit easy visualization of developmental events.  The available genetic and molecular tools permit detailed molecular studies to be undertaken.  Because the embryos develop externally, they can be injected with synthetic nucleotide constructs or treated with metabolic inhibitors added to their tank water.  The effects of the treatment can be evaluated without potentially complicating effects on the mother such as those encountered with mammalian models.

 


Movies:

Below are downloadable movies in which you can see the embryonic development of a zebrafish. Please note that you need a media player that supports .mpg files in order to view these movies.

Description: 4 embryos developing from 2 to 24 hours post fertilization. (Size: 890 Kb)

 

Description: 2 embryos developing from 1 to 24 hours post fertilization. (Size: 1.09 Mb)

 

Description: A single embryo developing from 2 to 24 hours post fertilization. (Size: 2.36 Mb)

 

Description: Somite development from 10 to 24 hours post fertilization. (Size: 2.14 Mb)


MRI Scans of Adult Zebrafish Cross Sections